Clik here to view.
How Many People Have Eosinophilic Esophagitis?
Eosinophilic esophagitis (EoE), which was barely recognized 20 years ago, affects at least 150,000 people in the United States, with three-quarters being adults, report Evan Dellon et al. in the April...
View ArticleWhat is the Best Strategy for Treating Pediatric Autoimmune Hepatitis?
Immunosuppressant therapy causes permanent recovery from liver failure in most children with autoimmune hepatitis (AIH), reports Miriam Cuarterolo et al. in the February issue of Clinical...
View ArticleClik here to view.
Tracking Crohn’s Therapy
Measuring blood levels of C-reactive protein (CRP), a marker of inflammation, is a good way to monitor recovery from Crohn’s disease (CD) in patients being treated with infliximab, according to...
View ArticleClik here to view.
What Causes Pancreatitis?
Trypsinogen might not be the sole culprit in acute pancreatitis, contradicting a century-old model of this disease; a new model is published in the December issue of Gastroenterology. Trypsinogen is a...
View ArticleClik here to view.
Eosinophilic Esophagitis? Change Your Diet.
Eliminating specific foods from your diet can reduce symptoms of eosinophilic esophagitis (EoE), according to the June issue of Gastroenterology. EoE is an immune disorder in which eosinophils cause...
View ArticleClik here to view.
What are the Effects of Albumin in Patients With SBP?
Albumin infusion prevents renal impairment and reduces mortality among patients with spontaneous bacterial peritonitis (SBP), according to a meta-analysis published in the February issue of Clinical...
View ArticleHow Does PSC Lead to IBD?
Many patients with primary sclerosing cholangitis (PSC) also have inflammatory bowel disease (IBD), which becomes more severe after liver transplantation, researchers report in the May issue of...
View ArticleClik here to view.
What is the Best Way to Care for Patients with Alcoholic Hepatitis?
Although alcohol-related liver disease is the 8th most common cause of mortality in the US and the 2nd leading cause of mortality among all gastrointestinal diseases, there are few therapeutic options...
View ArticleClik here to view.
Can Dietary Changes Reduce Eosinophilic Esophagitis in Adults?
Dietary elimination is a successful treatment approach for adults with eosinophilic esophagitis (EoE), researchers report in the August issue of Clinical Gastroenterology and Hepatology. EoE is...
View ArticleClik here to view.
What are the Roles for Chemokines in Liver Disease?
Sustained hepatic inflammation contributes to the progression of chronic liver diseases such as hepatitis C and non-alcoholic steatohepatitis. In the September issue of Gastroenterology, Fabio Marra...
View ArticleClik here to view.
Restoring Immune Regulation to Patients With Alcoholic Hepatitis
Patients with alcoholic hepatitis have dysfunctional T-cell and natural killer cell responses that lead to overwhelming bacterial infections. Researchers report in the March issue of Gastroenterology...
View ArticleGut Microbiome Determines Efficacy of Cancer Immunotherapy
Specific groups of intestinal microbes can boost the anti-tumor effects of cancer immunotherapies in mice, researchers show. Cancer immunotherapies that block immune inhibitory pathways have been...
View ArticleClik here to view.
Is Combination Therapy Most Effective for HBV Infection?
A significantly greater proportion of patients receiving a combination of tenofovir disoproxil fumarate (TDF) and pegylated interferon-α (peginterferon) for 48 weeks lost hepatitis B surface antigen...
View ArticleClik here to view.
Peanut Consumption in Infancy not Only Prevents Allergy but Effects Persist...
The benefits of regularly consuming peanut-containing foods early in life to prevent the development of peanut allergy persist even when subjects stopped peanut consumption for 1 year, a clinical study...
View ArticleClik here to view.
How Could the Intestinal Microbiota Contribute to Celiac Disease?
Bacteria in the small intestine metabolize gluten differently, to increase or decrease its immunogenicity, researchers report in the October issue of Gastroenterology. This interaction between microbes...
View ArticleClik here to view.
How Does Inflammation Lead to Anemia?
Researchers report a mechanism by which inflammation contributes to development of anemia in the November issue of Gastroenterology. The process involves increased liver expression of a microRNA that...
View ArticleClik here to view.
How Does Cigarette Smoking Lead to Chronic Pancreatitis?
Aryl hydrocarbons in cigarette smoke activate an immune response that promotes pancreatic fibrosis and contributes to pancreatitis, researchers report in the December issue of Gastroenterology. The...
View ArticleClik here to view.
Hepatosplenic Lesions from Cat Scratch Disease
Researchers describe an unusual case of cat scratch disease, with hepatosplenic involvement, in the January 2017 issue of Clinical Gastroenterology and Hepatology. Sean K. Verma et al report on a...
View ArticleClik here to view.
What are the Different Types of Liver Cancer, and How do They Develop?
A review article in the March issue of Gastroenterology discusses different hypotheses about the cells responsible for liver tumorigenesis. The article also reviews the different classes of liver...
View ArticleClik here to view.
What Causes Wheat Sensitivity in People Without Celiac Disease?
Gluten-containing cereals have high concentrations of amylase-trypsin inhibitors (ATIs), which activate innate immunity via the toll-like receptor 4 (TLR4), researchers report in the April issue of...
View ArticleClik here to view.
3-D Imaging of T-cell Localization in Inflamed Colon Tissues
Light sheet fluorescence microscopy (LSFM) provides accurate 3-dimensional images of inflammed intestine of mice with colitis, researchers show in a Gastroenterology in Motion article and video in the...
View ArticleClik here to view.
How Could Lamins Protect Against Steatohepatitis?
Lamin A/C acts maintains hepatocyte nuclear shape and protects male mice from steatohepatitis by regulating growth hormone signaling and reducing activity of STAT1, researchers report in the November...
View ArticleClik here to view.
Intestinal Microbes as Carcinogens
Fecal microbiota from patients with colorectal cancer (CRC) have carcinogenic properties, researchers report in the December issue of Gastroenterology. Feeding mice stool from patients with colorectal...
View ArticleClik here to view.
Does Immunomodulator Therapy for IBD During Pregnancy Affect Newborn Response...
Rates of adequate serologic response to Haemophilus influenzae B (HiB) and tetanus vaccines are similar among infants born to women with inflammatory bowel diseases (IBD) treated with immunomodulator...
View ArticleClik here to view.
Review: How Does the Tumor Stroma Contribute to Pancreatic Cancer...
Recently developed approaches for reshaping the pancreatic tumor stroma might be used in treatments for pancreatic cancer, according to a review in the March issue of Gastroenterology. The authors...
View ArticleClik here to view.
Does Acute Pancreatitis Increase Risk of Pancreatic Cancer?
Patients hospitalized with acute pancreatitis have a 2-fold increased risk of pancreatic cancer compared with the general population, researchers report in the May issue of Gastroenterology. Cumulative...
View ArticleClik here to view.
How Is The Intestinal Microbiome Altered in Patients With IBD and Does it...
Treatment of inflammatory bowel diseases (IBD) with anti-tumor necrosis factor (anti-TNF) drugs restores diversity to the intestinal microbiome, researchers report in the November issue of...
View ArticleClik here to view.
Is Red Wine Consumption Good for Your Intestinal Microbiome?
Consumption of red wine increases gut health, based on α-diversity of the intestinal microbiome, researchers report in the January 2020 issue of Gastroenterology. White wine had only weak effects,...
View ArticleClik here to view.
Corticosteroids, but not TNF Antagonists, Associate With Adverse COVID-19...
Increasing age, comorbidities, and use of corticosteroids and other anti-inflammatory agents correlated with severe COVID-19 in patients with inflammatory bowel diseases (IBD), whereas treatment with...
View Article
